Codon 104 variation of p53 gene provides adaptive apoptotic responses to extreme environments in mammals of the Tibet plateau

Mutational changes in p53 correlate well with tumorigenesis. Remarkably, however, relatively little is known about the role that p53 variations may play in environmental adaptation. Here we report that codon asparagine-104 (104N) and glutamic acid-104 (104E), respectively, of the p53 gene in the wil...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhao, Yang, Ren, Ji-Long, Wang, Ming-Yang, Zhang, Sheng-Ting, Liu, Yu, Li, Min, Cao, Yi-Bin, Zu, Hu-Yue, Chen, Xiao-Cheng, Wu, Chung-I, Nevo, Eviatar, Chen, Xue-Qun, Du, Ji-Zeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870672/
https://ncbi.nlm.nih.gov/pubmed/24297887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320369110
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