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A Biophysically-based Mathematical Model for the Catalytic Mechanism of Glutathione Reductase

Glutathione reductase (GR) catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the reducing cofactor, and thereby maintains a constant GSH level in the system. GSH scavenges superoxide (O(2)(·−)) and hydroxyl radicals (OH(·)) non-enzymatically or by ser...

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Detaylı Bibliyografya
Asıl Yazarlar: Pannala, Venkat R., Bazil, Jason N., Camara, Amadou K.S., Dash, Ranjan K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870161/
https://ncbi.nlm.nih.gov/pubmed/24120751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.10.001
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