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A Biophysically-based Mathematical Model for the Catalytic Mechanism of Glutathione Reductase
Glutathione reductase (GR) catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the reducing cofactor, and thereby maintains a constant GSH level in the system. GSH scavenges superoxide (O(2)(·−)) and hydroxyl radicals (OH(·)) non-enzymatically or by ser...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870161/ https://ncbi.nlm.nih.gov/pubmed/24120751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.10.001 |
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