Loading...

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.

We have isolated a human cytomegalovirus mutant that is resistant to the antiviral drug 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U), yet exhibits wild-type sensitivity to inhibitors of herpesvirus DNA polymerases such as phosphonoformic acid and aphidicolin. Cells infected with t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Biron, K K, Fyfe, J A, Stanat, S C, Leslie, L K, Sorrell, J B, Lambe, C U, Coen, D M
Format: Artigo
Sprog:Inglês
Udgivet: 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC387013/
https://ncbi.nlm.nih.gov/pubmed/3022304
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!