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Stereoselective Formation of Mono- and Di-Hydroxylated Polychlorinated Biphenyls by Rat Cytochrome P450 2B1

Changes in atropisomer composition of chiral polychlorinated biphenyls (PCBs) and their mono- and di- hydroxylated metabolites (OH- and diOH-PCBs) via rat cytochrome P450 2B1 (CYP2B1) mediated biotransformation were investigated in vitro. Rat CYP2B1 could stereoselectively biotransform chiral PCBs t...

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Hlavní autoři: Lu, Zhe, Kania-Korwel, Izabela, Lehmler, Hans-Joachim, Wong, Charles S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870094/
https://ncbi.nlm.nih.gov/pubmed/24060104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es402838f
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