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GAS CHROMATOGRAPHIC ANALYSIS WITH CHIRAL CYCLODEXTR IN PHASES REVEALS THE ENANTIOSELECTIVE FORMATION OF HYDROXYLATED POLYCHLORINATED BIPHENYLS BY RAT LIVER MICROSOMES

Chiral PCB congeners are major components of PCB mixtures and undergo enantioselective biotransformation to hydroxylated (OH-)PCBs by cytochrome P450 enzymes. While it is known that biotransformation results in an enantiomeric enrichment of the parent PCB, it is currently unknown if OH-PCBs are form...

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Detalhes bibliográficos
Main Authors: Kania-Korwel, Izabela, Duffel, Michael W., Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216237/
https://ncbi.nlm.nih.gov/pubmed/21966948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es2014727
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