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GAS CHROMATOGRAPHIC ANALYSIS WITH CHIRAL CYCLODEXTR IN PHASES REVEALS THE ENANTIOSELECTIVE FORMATION OF HYDROXYLATED POLYCHLORINATED BIPHENYLS BY RAT LIVER MICROSOMES

Chiral PCB congeners are major components of PCB mixtures and undergo enantioselective biotransformation to hydroxylated (OH-)PCBs by cytochrome P450 enzymes. While it is known that biotransformation results in an enantiomeric enrichment of the parent PCB, it is currently unknown if OH-PCBs are form...

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Bibliografiska uppgifter
Huvudupphovsmän: Kania-Korwel, Izabela, Duffel, Michael W., Lehmler, Hans-Joachim
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216237/
https://ncbi.nlm.nih.gov/pubmed/21966948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es2014727
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