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Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

Interleukin 1 (IL-1) is a polypeptide released by activated macrophages and is thought to be a key mediator of host responses to infection and inflammation. The availability of highly purified and recombinant material has now permitted the evaluation of IL-1 as a mediator of chronic inflammatory pro...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Pettipher, E R, Higgs, G A, Henderson, B
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3490671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8749
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