Expression of major histocompatibility complex class I antigens as a strategy for the potentiation of immune recognition of tumor cells.

Like many primary tumors, human adenovirus type 12 (Ad12)-transformed mouse cells express greatly reduced levels of the major histocompatibility complex (MHC) class I antigens and are highly tumorigenic in immunocompetent hosts. Expression of a transfected class I gene by these cells can abrogate th...

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Bibliographic Details
Main Authors: Tanaka, K, Hayashi, H, Hamada, C, Khoury, G, Jay, G
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC387003/
https://ncbi.nlm.nih.gov/pubmed/3464979
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