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Expression of major histocompatibility complex class I antigens as a strategy for the potentiation of immune recognition of tumor cells.

Like many primary tumors, human adenovirus type 12 (Ad12)-transformed mouse cells express greatly reduced levels of the major histocompatibility complex (MHC) class I antigens and are highly tumorigenic in immunocompetent hosts. Expression of a transfected class I gene by these cells can abrogate th...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Tanaka, K, Hayashi, H, Hamada, C, Khoury, G, Jay, G
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464979/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8723
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