CD8(+) Cells Regulate the T helper-17 Response in an Experimental Murine Model of Sjögren Syndrome

This study investigated the regulatory function of CD8(+) cells in T helper (Th) 17 cell-mediated corneal epithelial barrier disruption that develops in a murine desiccating stress (DS) model that resembles Sjögren syndrome. CD8(+) cell depletion promoted generation of IL-17A producing CD4(+) T cell...

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Hauptverfasser: Zhang, X., Schaumburg, C.S., Coursey, T.G., Siemasko, K.F., Volpe, E. A., Gandhi, N.B., Li, D.-Q., Niederkorn, J.Y., Stern, M.E., Pflugfelder, S.C., de Paiva, C.S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869878/
https://ncbi.nlm.nih.gov/pubmed/24022789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.61
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