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Wound Healing Improvement with PHD-2 Silenced Fibroblasts in Diabetic Mice
BACKGROUND: Hypoxia-inducible factor 1α is the central regulator of the hypoxia-induced response which results in the up-regulation of angiogenic factors. Its activity is under precise regulation of prolyl-hydroxylase domain 2. We hypothesized that PHD2 silenced fibroblasts would increase the expres...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869847/ https://ncbi.nlm.nih.gov/pubmed/24376825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084548 |
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