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Wound Healing Improvement with PHD-2 Silenced Fibroblasts in Diabetic Mice

BACKGROUND: Hypoxia-inducible factor 1α is the central regulator of the hypoxia-induced response which results in the up-regulation of angiogenic factors. Its activity is under precise regulation of prolyl-hydroxylase domain 2. We hypothesized that PHD2 silenced fibroblasts would increase the expres...

詳細記述

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書誌詳細
主要な著者: Zhang, Xiongliang, Yan, Xiaoyu, Cheng, Liang, Dai, Jiezhi, Wang, Chunyang, Han, Pei, Chai, Yimin
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869847/
https://ncbi.nlm.nih.gov/pubmed/24376825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084548
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