Proof of the Concept to Use a Malignant B Cell Line Drug Screen Strategy for Identification and Weight of Melphalan Resistance Genes in Multiple Myeloma

In a conceptual study of drug resistance we have used a preclinical model of malignant B-cell lines by combining drug induced growth inhibition and gene expression profiling. In the current report a melphalan resistance profile of 19 genes were weighted by microarray data from the MRC Myeloma IX tri...

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Detalhes bibliográficos
Main Authors: Bøgsted, Martin, Bilgrau, Anders E., Wardell, Christopher P., Bertsch, Uta, Schmitz, Alexander, Bødker, Julie S., Kjeldsen, Malene K., Goldschmidt, Hartmut, Morgan, Gareth J., Dybkaer, Karen, Johnsen, Hans E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869769/
https://ncbi.nlm.nih.gov/pubmed/24376673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083252
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