Membrane Cholesterol Removal Changes Mechanical Properties of Cells and Induces Secretion of a Specific Pool of Lysosomes

In a previous study we had shown that membrane cholesterol removal induced unregulated lysosomal exocytosis events leading to the depletion of lysosomes located at cell periphery. However, the mechanism by which cholesterol triggered these exocytic events had not been uncovered. In this study we inv...

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Main Authors: Hissa, Barbara, Pontes, Bruno, Roma, Paula Magda S., Alves, Ana Paula, Rocha, Carolina D., Valverde, Thalita M., Aguiar, Pedro Henrique N., Almeida, Fernando P., Guimarães, Allan J., Guatimosim, Cristina, Silva, Aristóbolo M., Fernandes, Maria C., Andrews, Norma W., Viana, Nathan B., Mesquita, Oscar N., Agero, Ubirajara, Andrade, Luciana O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869752/
https://ncbi.nlm.nih.gov/pubmed/24376622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082988
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