Membrane Cholesterol Regulates Lysosome-Plasma Membrane Fusion Events and Modulates Trypanosoma cruzi Invasion of Host Cells

BACKGROUND: Trypomastigotes of Trypanosoma cruzi are able to invade several types of non-phagocytic cells through a lysosomal dependent mechanism. It has been shown that, during invasion, parasites trigger host cell lysosome exocytosis, which initially occurs at the parasite-host contact site. Acid...

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Detalhes bibliográficos
Main Authors: Hissa, Bárbara, Duarte, Jacqueline G., Kelles, Ludmila F., Santos, Fabio P., del Puerto, Helen L., Gazzinelli-Guimarães, Pedro H., de Paula, Ana M., Agero, Ubirajara, Mesquita, Oscar N., Guatimosim, Cristina, Chiari, Egler, Andrade, Luciana O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3313932/
https://ncbi.nlm.nih.gov/pubmed/22479662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001583
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