Use of Net Reclassification Improvement (NRI) Method Confirms The Utility of Combined Genetic Risk Score to Predict Type 2 Diabetes

BACKGROUND: Recent genome-wide association studies (GWAS) identified more than 70 novel loci for type 2 diabetes (T2D), some of which have been widely replicated in Asian populations. In this study, we investigated their individual and combined effects on T2D in a Chinese population. METHODOLOGY: We...

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Main Authors: Tam, Claudia H. T., Ho, Janice S. K., Wang, Ying, Lam, Vincent K. L., Lee, Heung Man, Jiang, Guozhi, Lau, Eric S. H., Kong, Alice P. S., Fan, Xiaodan, Woo, Jean L. F., Tsui, Stephen K. W., Ng, Maggie C. Y., So, Wing Yee, Chan, Juliana C. N., Ma, Ronald C. W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869744/
https://ncbi.nlm.nih.gov/pubmed/24376643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083093
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