Use of Net Reclassification Improvement (NRI) Method Confirms The Utility of Combined Genetic Risk Score to Predict Type 2 Diabetes

BACKGROUND: Recent genome-wide association studies (GWAS) identified more than 70 novel loci for type 2 diabetes (T2D), some of which have been widely replicated in Asian populations. In this study, we investigated their individual and combined effects on T2D in a Chinese population. METHODOLOGY: We...

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Bibliografiska uppgifter
Huvudupphovsmän: Tam, Claudia H. T., Ho, Janice S. K., Wang, Ying, Lam, Vincent K. L., Lee, Heung Man, Jiang, Guozhi, Lau, Eric S. H., Kong, Alice P. S., Fan, Xiaodan, Woo, Jean L. F., Tsui, Stephen K. W., Ng, Maggie C. Y., So, Wing Yee, Chan, Juliana C. N., Ma, Ronald C. W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869744/
https://ncbi.nlm.nih.gov/pubmed/24376643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083093
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