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Polyadenylylation of an mRNA precursor occurs independently of transcription by RNA polymerase II in vivo.

Most eukaryotic messenger RNAs are transcribed as precursor molecules that must be processed by capping, splicing, 3' cleavage, and polyadenylylation to yield mature mRNAs. An important, unresolved issue is whether any of these reactions are linked either to transcription by RNA polymerase II or to...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lewis, E D, Manley, J L
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1986
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2877459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8555
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