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Polyadenylylation of an mRNA precursor occurs independently of transcription by RNA polymerase II in vivo.

Most eukaryotic messenger RNAs are transcribed as precursor molecules that must be processed by capping, splicing, 3' cleavage, and polyadenylylation to yield mature mRNAs. An important, unresolved issue is whether any of these reactions are linked either to transcription by RNA polymerase II or to...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lewis, E D, Manley, J L
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386969/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2877459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8555
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