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Inferring Short-Range Linkage Information from Sequencing Chromatograms

Direct Sanger sequencing of viral genome populations yields multiple ambiguous sequence positions. It is not straightforward to derive linkage information from sequencing chromatograms, which in turn hampers the correct interpretation of the sequence data. We present a method for determining the var...

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Main Authors: Beggel, Bastian, Neumann-Fraune, Maria, Kaiser, Rolf, Verheyen, Jens, Lengauer, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869653/
https://ncbi.nlm.nih.gov/pubmed/24376502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081687
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