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Inferring Short-Range Linkage Information from Sequencing Chromatograms

Direct Sanger sequencing of viral genome populations yields multiple ambiguous sequence positions. It is not straightforward to derive linkage information from sequencing chromatograms, which in turn hampers the correct interpretation of the sequence data. We present a method for determining the var...

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Detalhes bibliográficos
Main Authors: Beggel, Bastian, Neumann-Fraune, Maria, Kaiser, Rolf, Verheyen, Jens, Lengauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869653/
https://ncbi.nlm.nih.gov/pubmed/24376502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081687
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