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Inferring Short-Range Linkage Information from Sequencing Chromatograms

Direct Sanger sequencing of viral genome populations yields multiple ambiguous sequence positions. It is not straightforward to derive linkage information from sequencing chromatograms, which in turn hampers the correct interpretation of the sequence data. We present a method for determining the var...

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Detalles Bibliográficos
Main Authors: Beggel, Bastian, Neumann-Fraune, Maria, Kaiser, Rolf, Verheyen, Jens, Lengauer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869653/
https://ncbi.nlm.nih.gov/pubmed/24376502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081687
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