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Inferring Short-Range Linkage Information from Sequencing Chromatograms

Direct Sanger sequencing of viral genome populations yields multiple ambiguous sequence positions. It is not straightforward to derive linkage information from sequencing chromatograms, which in turn hampers the correct interpretation of the sequence data. We present a method for determining the var...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beggel, Bastian, Neumann-Fraune, Maria, Kaiser, Rolf, Verheyen, Jens, Lengauer, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869653/
https://ncbi.nlm.nih.gov/pubmed/24376502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081687
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