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Molecular pathogenesis of AML: Translating insights to the clinic
Specific combinations of mutations, including FLT3 and IDH1/IDH2/TET2, frequently co-occur in acute myeloid leukemia (AML) and are associated with poor prognosis. These mutation combinations can be modeled in mice to provide a more genetically accurate model of AML. Within these models, stem cells m...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869618/ https://ncbi.nlm.nih.gov/pubmed/24309525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beha.2013.10.003 |
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