Regulation of CYP3A genes by glucocorticoids in human lung cells

Inhaled glucocorticoids are the first-line treatment for patients with persistent asthma.  However, approximately thirty percent of patients exhibit glucocorticoid insensitivity, which may involve excess metabolic clearance of the glucocorticoids by CYP3A enzymes in the lung.  CYP3A4, 3A5, and 3A7 e...

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Detaylı Bibliyografya
Asıl Yazarlar: Roberts, Jessica K, Moore, Chad D, Romero, Erin G, Ward, Robert M, Yost, Garold S, Reilly, Christopher A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: F1000Research 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869485/
https://ncbi.nlm.nih.gov/pubmed/24555085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-173.v2
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