Specific modulation of sodium channels in mammalian nerve by monoclonal antibodies.

Monoclonal antibodies (mAbs) were generated against the sodium channels in the intact membrane of the eel electroplax. These antibodies bind to nodes of Ranvier, as indicated by immunofluorescence. When externally applied to rat nerve fibers one of these mAbs blocks impulse conduction. In voltage-cl...

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Библиографические подробности
Главные авторы: Meiri, H, Goren, E, Bergmann, H, Zeitoun, I, Rosenthal, Y, Palti, Y
Формат: Artigo
Язык:Inglês
Опубликовано: 1986
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC386933/
https://ncbi.nlm.nih.gov/pubmed/2430287
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