Monoclonal antibody specific for an activated RAS protein.

Activated RAS transforming genes that encode proteins (p21s) with amino acid substitutions at positions 12, 13, or 61 have been detected in 10-20% of human neoplasms. This report describes a monoclonal antibody (DWP) raised against a synthetic peptide corresponding to amino acids 5-16 of a mutated R...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Carney, W P, Petit, D, Hamer, P, Der, C J, Finkel, T, Cooper, G M, Lefebvre, M, Mobtaker, H, Delellis, R, Tischler, A S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3094010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7485
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