Monoclonal antibody specific for an activated RAS protein.

Activated RAS transforming genes that encode proteins (p21s) with amino acid substitutions at positions 12, 13, or 61 have been detected in 10-20% of human neoplasms. This report describes a monoclonal antibody (DWP) raised against a synthetic peptide corresponding to amino acids 5-16 of a mutated R...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Carney, W P, Petit, D, Hamer, P, Der, C J, Finkel, T, Cooper, G M, Lefebvre, M, Mobtaker, H, Delellis, R, Tischler, A S
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1986
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3094010/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7485
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