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An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P(2)O(5) and catalyzed by zinc bromide

A self-condensation cyclization reaction mediated by phosphorus pentoxide (P(2)O(5)) and catalyzed by zinc bromide (ZnBr(2)) is presented for the synthesis of polysubstituted 4-pyridones and 2-pyridones from β-keto amides. A variety of β-keto amides are used in this approach, and a wide range of fun...

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Detalhes bibliográficos
Main Authors: Tan, Liquan, Zhou, Peng, Chen, Cui, Liu, Weibing
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869214/
https://ncbi.nlm.nih.gov/pubmed/24367433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.304
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