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An efficient method for the construction of polysubstituted 4-pyridones via self-condensation of β-keto amides mediated by P(2)O(5) and catalyzed by zinc bromide
A self-condensation cyclization reaction mediated by phosphorus pentoxide (P(2)O(5)) and catalyzed by zinc bromide (ZnBr(2)) is presented for the synthesis of polysubstituted 4-pyridones and 2-pyridones from β-keto amides. A variety of β-keto amides are used in this approach, and a wide range of fun...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Beilstein-Institut
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869214/ https://ncbi.nlm.nih.gov/pubmed/24367433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.304 |
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