Genetic basis for the cross-reactive idiotypes on the light chains of human IgM anti-IgG autoantibodies.

The role of immunoglobulin structural genes in the generation of autoantibodies in humans has not been elucidated. Human monoclonal IgM anti-IgG autoantibodies (rheumatoid factors, RFs) from unrelated people often share idiotypic antigens. Antibodies against synthetic peptides have localized two of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chen, P P, Albrandt, K, Orida, N K, Radoux, V, Chen, E Y, Schrantz, R, Liu, F T, Carson, D A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3095834/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8318
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