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The α4 Nicotinic Receptor Promotes CD4(+) T-Cell Proliferation and a Helper T-Cell Immune Response

Smoking is a common addiction and a leading cause of disease. Chronic nicotine exposure is known to activate nicotinic acetylcholine receptors (nAChRs) in immune cells. We demonstrate a novel role for α4 nAChRs in the effect of nicotine on T-cell proliferation and immunity. Using cell-based sorting...

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Detalhes bibliográficos
Main Authors: Nordman, Jacob C., Muldoon, Pretal, Clark, Sarah, Damaj, M. Imad, Kabbani, Nadine
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868899/
https://ncbi.nlm.nih.gov/pubmed/24107512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.088484
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