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The α4 Nicotinic Receptor Promotes CD4(+) T-Cell Proliferation and a Helper T-Cell Immune Response
Smoking is a common addiction and a leading cause of disease. Chronic nicotine exposure is known to activate nicotinic acetylcholine receptors (nAChRs) in immune cells. We demonstrate a novel role for α4 nAChRs in the effect of nicotine on T-cell proliferation and immunity. Using cell-based sorting...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868899/ https://ncbi.nlm.nih.gov/pubmed/24107512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.088484 |
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