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The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse

The 15q25 gene cluster contains genes that code for the α5, α3, and β4 nicotinic acetylcholine receptor (nAChRs) subunits, and in human genetic studies, has shown the most robust association with smoking behavior and nicotine dependence to date. The limited available animal studies implicate a role...

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Hlavní autoři: Jackson, Kia J., Sanjakdar, Sarah S., Muldoon, Pretal P., McIntosh, J. Michael, Damaj, M. Imad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644352/
https://ncbi.nlm.nih.gov/pubmed/23416040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.01.017
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