Mitogen-activated Protein Kinase Signaling Mediates Phosphorylation of Polycomb Ortholog Cbx7

Cbx7 is one of five mammalian orthologs of the Drosophila Polycomb. Cbx7 recognizes methylated lysine residues on the histone H3 tail and contributes to gene silencing in the context of the Polycomb repressive complex 1 (PRC1). However, our knowledge of Cbx7 post-translational modifications remains...

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Autors principals: Wu, Hsan-au, Balsbaugh, Jeremy L., Chandler, Hollie, Georgilis, Athena, Zullow, Hayley, Shabanowitz, Jeffrey, Hunt, Donald F., Gil, Jesus, Peters, Gordon, Bernstein, Emily
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868753/
https://ncbi.nlm.nih.gov/pubmed/24194518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.486266
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