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Highly Specific PET Imaging of Prostate Tumors in Mice with an Iodine-124-Labeled Antibody Fragment That Targets Phosphatidylserine

Phosphatidylserine (PS) is an attractive target for imaging agents that identify tumors and assess their response to therapy. PS is absent from the surface of most cell types, but becomes exposed on tumor cells and tumor vasculature in response to oxidative stresses in the tumor microenvironment and...

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Main Authors: Stafford, Jason H., Hao, Guiyang, Best, Anne M., Sun, Xiankai, Thorpe, Philip E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868598/
https://ncbi.nlm.nih.gov/pubmed/24367699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084864
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