Identification of Poly(ADP-Ribose) Polymerase-1 as a Cell Cycle Regulator through Modulating Sp1 Mediated Transcription in Human Hepatoma Cells

The transcription factor Sp1 is implicated in the activation of G0/G1 phase genes. Modulation of Sp1 transcription activities may affect G1-S checkpoint, resulting in changes in cell proliferation. In this study, our results demonstrated that activated poly(ADP-ribose) polymerase 1 (PARP-1) promoted...

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Detalhes bibliográficos
Main Authors: Yang, Liu, Huang, Kun, Li, Xiangrao, Du, Meng, Kang, Xiang, Luo, Xi, Gao, Lu, Wang, Cheng, Zhang, Yanqing, Zhang, Chun, Tong, Qiangsong, Huang, Kai, Zhang, Fengxiao, Huang, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868549/
https://ncbi.nlm.nih.gov/pubmed/24367566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082872
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