High Capacity Nanoporous Silicon Carrier for Systemic Delivery of Gene Silencing Therapeutics

Gene silencing agents such as small interfering RNA (siRNA) and microRNA offer the promise to modulate expression of almost every gene for the treatment of human diseases including cancer. However, lack of vehicles for effective systemic delivery to the disease organs has greatly limited their in vi...

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Hlavní autoři: Shen, Jianliang, Xu, Rong, Mai, Junhua, Kim, Han-Cheon, Guo, Xiaojing, Qin, Guoting, Yang, Yong, Wolfram, Joy, Mu, Chaofeng, Xia, Xiaojun, Gu, Jianhua, Liu, Xuewu, Mao, Zong-Wan, Ferrari, Mauro, Shen, Haifa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868485/
https://ncbi.nlm.nih.gov/pubmed/24131405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn4035316
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