Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation.

Interaction of the activated insulin receptor (IR) with its substrate, insulin receptor substrate 1 (IRS-1), via the phosphotyrosine binding domain of IRS-1 and the NPXY motif centered at phosphotyrosine 960 of the IR, is important for IRS-1 phosphorylation. We investigated the role of this interact...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Morris, A J, Martin, S S, Haruta, T, Nelson, J G, Vollenweider, P, Gustafson, T A, Mueckler, M, Rose, D W, Olefsky, J M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8401
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