Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation.

Interaction of the activated insulin receptor (IR) with its substrate, insulin receptor substrate 1 (IRS-1), via the phosphotyrosine binding domain of IRS-1 and the NPXY motif centered at phosphotyrosine 960 of the IR, is important for IRS-1 phosphorylation. We investigated the role of this interact...

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Main Authors: Morris, A J, Martin, S S, Haruta, T, Nelson, J G, Vollenweider, P, Gustafson, T A, Mueckler, M, Rose, D W, Olefsky, J M
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC38683/
https://ncbi.nlm.nih.gov/pubmed/8710883
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