Lymphokine-activated killer cells targeted by monoclonal antibodies to the disialogangliosides GD2 and GD3 specifically lyse human tumor cells of neuroectodermal origin.

Monoclonal antibodies 14.18 (IgG3) and 11C64 (IgG3) directed against disialogangliosides GD2 and GD3, respectively, when used in conjunction with human peripheral blood mononuclear cells (PBMCs) stimulated with human recombinant interleukin (rIL-2) lyse both human melanoma and neuroblastoma cells by...

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Bibliographic Details
Main Authors: Honsik, C J, Jung, G, Reisfeld, R A
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC386829/
https://ncbi.nlm.nih.gov/pubmed/3094017
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