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Transformation of a human poliovirus receptor gene into mouse cells.

The first step in poliovirus replication is binding of virus to a cellular receptor. Mouse L cells, which are resistant to poliovirus infection because they do not bear a poliovirus receptor, were transformed with HeLa cell (human) DNA to poliovirus sensitivity at a frequency of approximately 1 in 5...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Mendelsohn, C, Johnson, B, Lionetti, K A, Nobis, P, Wimmer, E, Racaniello, V R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386819/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3020560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7845
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