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"Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential.

Protooncogenes when transduced by retroviruses may undergo structural modifications that render their gene products oncogenic. The c-fms gene encodes a transmembrane protein with tyrosine kinase activity that is very similar or identical to the receptor for the monocyte-macrophage colony-stimulating...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Browning, P J, Bunn, H F, Cline, A, Shuman, M, Nienhuis, A W
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1986
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3532121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7800
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