"Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential.
Protooncogenes when transduced by retroviruses may undergo structural modifications that render their gene products oncogenic. The c-fms gene encodes a transmembrane protein with tyrosine kinase activity that is very similar or identical to the receptor for the monocyte-macrophage colony-stimulating...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1986
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3532121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7800 |
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