"Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential.

Protooncogenes when transduced by retroviruses may undergo structural modifications that render their gene products oncogenic. The c-fms gene encodes a transmembrane protein with tyrosine kinase activity that is very similar or identical to the receptor for the monocyte-macrophage colony-stimulating...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Browning, P J, Bunn, H F, Cline, A, Shuman, M, Nienhuis, A W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1986
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3532121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7800
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