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Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

Differences in susceptibility to diabetic nephropathy (DN) between mouse strains with identical levels of hyperglycemia correlate with renal levels of oxidative stress, shown previously to play a central role in the pathogenesis of DN. Susceptibility to DN appears to be genetically determined, but t...

詳細記述

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書誌詳細
主要な著者: Giacco, Ferdinando, Du, Xueliang, D’Agati, Vivette D., Milne, Ross, Sui, Guangzhi, Geoffrion, Michele, Brownlee, Michael
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868051/
https://ncbi.nlm.nih.gov/pubmed/24062246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0316
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