Soluble Factors Secreted by T Cells Promote β-Cell Proliferation

Type 1 diabetes is characterized by infiltration of pancreatic islets with immune cells, leading to insulin deficiency. Although infiltrating immune cells are traditionally considered to negatively impact β-cells by promoting their death, their contribution to proliferation is not fully understood....

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Main Authors: Dirice, Ercument, Kahraman, Sevim, Jiang, Wenyu, El Ouaamari, Abdelfattah, De Jesus, Dario F., Teo, Adrian K.K., Hu, Jiang, Kawamori, Dan, Gaglia, Jason L., Mathis, Diane, Kulkarni, Rohit N.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2014
Teme:
Islet Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868047/
https://ncbi.nlm.nih.gov/pubmed/24089508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0204
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