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Multiple HLA Epitopes Contribute to Type 1 Diabetes Susceptibility

Disease susceptibility for type 1 diabetes is strongly associated with the inheritance of specific HLA alleles. However, conventional allele frequency analysis can miss HLA associations because many alleles are rare. In addition, disparate alleles that have similar peptide-binding sites, or shared e...

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Hlavní autoři: Roark, Christina L., Anderson, Kirsten M., Simon, Lucas J., Schuyler, Ronald P., Aubrey, Michael T., Freed, Brian M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868045/
https://ncbi.nlm.nih.gov/pubmed/24357703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1153
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