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Multiple HLA Epitopes Contribute to Type 1 Diabetes Susceptibility

Disease susceptibility for type 1 diabetes is strongly associated with the inheritance of specific HLA alleles. However, conventional allele frequency analysis can miss HLA associations because many alleles are rare. In addition, disparate alleles that have similar peptide-binding sites, or shared e...

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Detalhes bibliográficos
Main Authors: Roark, Christina L., Anderson, Kirsten M., Simon, Lucas J., Schuyler, Ronald P., Aubrey, Michael T., Freed, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868045/
https://ncbi.nlm.nih.gov/pubmed/24357703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1153
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