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Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli.

Escherichia coli deficient in exonuclease III (xth gene mutants) are known to be hypersensitive to hydrogen peroxide. We now show that such mutants accumulate many more DNA single-strand breaks than do wild-type bacteria upon exposure to H2O2. DNA isolated from H2O2-treated xth- cells contains stran...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Demple, B, Johnson, A, Fung, D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2429316/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.20.7731
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