Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.
The p53 mutant, 143ala, was translated in vitro in either rabbit reticulocyte lysate (RRL) or wheat germ extract (WGE). In RRL, p53-143ala protein of both mutant and wild-type conformation, as detected immunologically with conformation-specific antibodies, was translated. The chaperone protein HSP90...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38679/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8710879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.16.8379 |
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