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Glucocerebrosidase processing in normal fibroblasts and in fibroblasts from patients with type I, type II, and type III Gaucher disease.

Fibroblasts from normal subjects and patients with the three types of Gaucher disease were labeled with [3H]leucine. Glucocerebrosidase antigen was immunoprecipitated using affinity-purified Sepharose-bound antibody. Normal cells initially formed a 60-kDa polypeptide antigen that was gradually repla...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Beutler, E, Kuhl, W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1986
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3463977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7472
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