Glucocerebrosidase processing in normal fibroblasts and in fibroblasts from patients with type I, type II, and type III Gaucher disease.

Fibroblasts from normal subjects and patients with the three types of Gaucher disease were labeled with [3H]leucine. Glucocerebrosidase antigen was immunoprecipitated using affinity-purified Sepharose-bound antibody. Normal cells initially formed a 60-kDa polypeptide antigen that was gradually repla...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Beutler, E, Kuhl, W
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1986
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3463977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.19.7472
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